A day in Cooperstown always includes cruising Route 20, the old pike that runs from Massachusetts to Pennsylvania and finally all the way to Oregon. It runs parallel to the NYS Thruway and Route 5, south of them by 20 miles along this stretch we used from Cazenovia to Richfield Springs.
Those other two highways run in the Mohawk River valley and along the southern edge of the lakebed of post-glacial Lake Iroquois. Route 20 is inland and hilly. Further west it drops into deep valleys between Cazenovia and Skaneateles, and then crosses the outlets of the Finger Lakes.
The topography makes for an interesting ride.